The SPP1 connection
نویسندگان
چکیده
منابع مشابه
Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating.
In many bacterial viruses and in certain animal viruses, the double-stranded DNA genome enters and exits the capsid through a portal gatekeeper. We report a pseudoatomic structure of a complete portal system. The bacteriophage SPP1 gatekeeper is composed of dodecamers of the portal protein gp6, the adaptor gp15, and the stopper gp16. The solution structures of gp15 and gp16 were determined by N...
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متن کاملFunctional analysis of the Bacillus subtilis bacteriophage SPP1 pac site.
Encapsidation of the DNA of the virulent Bacillus subtilis phage SPP1 follows a processive unidirectional headful-mechanism and initiates at a unique genomic location (pac). We have cloned a fragment of SPP1 DNA containing the pac site flanked by reporter genes into the chromosome of B. subtilis. Infection of such cells with SPP1 led to highly efficient packaging, initiated at the inserted pac ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 1995
ISSN: 0168-6445
DOI: 10.1016/0168-6445(94)00078-6